SnO₂hollow nanospheres were prepared by loading SnCl₄on the surface of carbonaceous polysaccharide microspheres used as template. During the loading process, different kinds of solvent (ethonal or dimethylfomamide) were used to disperse the carbonaceous polysaccharide microspheres and SnCl₄. Carbonaceous polysaccharide microspheres were synthesized from glucose solution by hydrothermal method at different temperature (190 or 180 ℃) for 8 h. Pd-doped SnO₂hollow nanospheres were also prepared by similar method for comparison. The surface morphology of SnO₂hollow nanosphere was characterized by scanning electronic microscopy. The sensing properties of the sensor devices using the as-prepared SnO₂hollow nanospheres to H₂were investigated at the optimal working temperature. The difference of the sensing properties could be attributed to the difference of the particle size for the synthesized SnO₂hollow spheres. The doping of Pd into the SnO₂hollow spheres could not only lower the working temperature, but also improve the response to the target gas.