A series of mixed potential type gas sensors using stabilized zirconia and M₃V₂O₈(M: Zn, Co and Ni) sensing electrode were fabricated and applied for detecting acetone at 600℃. Among the sensors utilizing these composite oxides (Zn₃V₂O₈, Co₃V₂O₈and Ni₃V₂O₈)-SEs prepared via a facile sol-gel method, the sensor attached with Zn3V2O8-SE exhibited the highest response to acetone at 600℃. Therefore, the present study mainly focused on acetone sensing performance for YSZ-based sensor using Zn₃V₂O₈SE at 600℃. Results showed that the sensor attached with Zn₃V₂O₈-SE could detect even 1 ppm acetone with an acceptable response. Moreover, AV of the sensor attached with Zn₃V₂O₈-SE exhibited segmentally linear relationship to the logarithm of acetone concentration in the ranges of 1-10 ppm and 10-400 ppm, which the sensitivities were -16 and -56 mV/decade, respectively. The present device also displayed good repeatability, small drifts in 30 days measured period, and the excellent sensitivity and relatively good selectivity in the presence of various interfering gases before and after 30 days high-temperature-aging of 600℃. Additionally, polarization curve was measured to further demonstrate the mixed potential mechanism.