A long-standing goal has been to create a high-energy transfer system for food safety detection. Herein, gold nanoclusters-anchored manganese dioxide (AuNCs@MnO₂) nanocomposites are designed by using co-template assembly. Bovine serum albumin is utilized as both skeletons of nucleation and stabilizer to guide the synthesis of the AuNCs@MnO₂nanocomposites under physiological conditions without the use of any potent oxidants and the hazardous organic solvent. The AuNCs@MnO₂nanocomposites exhibit good energy transfer efficiency and structural stability even under high salt conditions and a wide range of pH values. A sensitive sensing platform for the detection of methyl paraoxon has been constructed as a result of the excellent performance of AuNCs@MnO₂nanocomposites. Acetylcholinesterase catalyzes the conversion of the substrate to produce thiocholine, which induces the decomposition of MnO₂and the fluorescence recovery of AuNCs. Coupling with the pesticide inhibition effect, the platform can be employed to quantify methyl parathion with a detection limit of 3.1 pg mL⁻¹. The AuNCs@MnO₂-based platform displays high stability and anti-interference capability in food and environment samples, endowing practical application in food safety monitoring.

原文链接：https://doi.org/10.1016/j.snb.2023.134736